Our Pulmonary Analysis Software Suite has been developed by in house programmers. It is a comprehensive package for the manipulation, display and analysis of multidimensional image data sets. PASS is intended to assist doctors and researchers in the field of pulmonary research with lung segmentation, histogram analysis, hole measurement, and nodules and tissue classification.
As VIDA's organically-developed software application, Apollo®, has evolved for over 10 years with extensive validation in marquis clinical trials and research institutions. Apollo has significant algorithmic, workflow and automation features applicable to high volume, repeatable parenchymal, airway, and fissure integrity analysis. VIDA believes that understanding the analysis software to its very core is imperative for high quality so they only use their own applications.
Multiscale imaging-based lung model suite (MSILung) is an integrative computational framework that comprises a multi-scale geometric modeling code. MSILung is multi-scale
in three aspects:
1. bridging central and peripheral airways and linking structure and function
2. bridging organ and cellular (or molecular) scales
3. bridging individual and population scales
The University of Iowa Carver College of Medicine has constructed a 2500 square foot CT imaging research facility for the support of the research efforts of the Iowa Comprehensive Lung Imaging Center, I-Clic. This spot is located strategically between the patient areas of the University of Iowa Hospitals and Clinics, the NIH supported Clinical Research Center, and the Animal Care Facilities of the College of Medicine. The space has been designed with a large control room, a MDCT scanner suite, a human preparation area, an animal preparation area, and a micro-CT room with an adjacent separate control room. The CT Scanning Research Facility is equipped with Polycom cameras within the CT suite, CT control room, animal surgery suite, and micro CT suite. It has a Polycom Server that allows multi-point conferencing and the ability for any of the remote sites to participate in live experiments. A Philips physiological monitoring system has been installed to match that in the Medical Intensive Care Unit in the University of Iowa Hospital. Data from the physiologic monitoring system are fed to a monitoring system running LabView software that interprets the physiology and sends signals to the MDCT scanner such that images are captured at a precise point within the physiologic signal of interest. The CT control room has a fifteen foot observation window into the CT suite, a conference table, and 7 computer equipped carrels for visiting scientists, the CT technologist and a study coordinator. Other major equipment includes Xe gas re- breathing delivery system (Diversified Diagnostic Products, Windfern, TX) high pressure Medrad Stellant contrast injector, a dual headed Bracco contrast injector, and a mobile digital fluoroscopy unit, allowing catheterization procedures in the scanner, human and animal preparation suites and at the scanner table. The facility includes a custom-built dual piston system that controls inspiration and expiration during human scanning such that exactly similar volumes of gas (xenon mixture) and exhalate are inspired from and exhaled into the two pistons with valves under computer control.
In addition to our CT lab area, there is a separate new space located immediately above for housing our computer clusters, large array data storage racks. Directly opposite the computer facility is the Environmental Health Sciences Research Center Exposure Chamber Facility with associated pulmonary function lab. Dr. Hoffman is the director of this facility. A few doors down is a dedicated fully equipped pulmonary function laboratory, including a body box (Nspire) and a gas chromatograph, allowing correlative studies using the Multiple Inert Gas Elimination Technique (MIGET). On this floor, as well as 2 floors above, resides the NIH supported CTSA Clinical Research Center. In addition, the I-CLIC has a customized microscopy facility with what has been dubbed the LIMA system consisting of a large stage microtome and microscope linked by computer control such that the cut surface of a specimen is digitized at microscopic resolution, the surface is scanned and images are merged before a thin section is cut, the microtome stage is adjusted such that the new surface remains in focus and the process is repeated. Dr. Hoffman's 2,500 square foot office and image analysis space reside on the 7th floor above the scanner facility.
Medical Imaging File Archive Recovery - MIFAR - is a set of software tools for storing medical image data along with other associated post-image processing files, physiologic records, and lab notes.
Procedural Verification Software is an automated web portal system for tracking and verifying data for multi-center studies. It provides a mechanism for obtaining information from scans including deviations and scan parameters as well as the appropriate dose for a given visit. PVS users are able to register subjects for their site in the database, communicate with the Radiology Reading Center via messaging system, and view details of previous scans performed by their site.
Perform perfusion and ventilation (blood-flow) analysis. Developed within our lab. The name stands for Time Series Image Analysis. It is cross-platform so it functions on Windows, Mac OSX, and Linux. The concept of TSIA was developed in the early 1990's. Algorithm modules for perfusion/ventilation parameter calculation are separated from GUI and they are built as a dynamic link library. Therefore, any algorithm dll can be switched depending on the data set at runtime. This enables algorithm developers to easily create their own algorithms for your analysis.